Product references — Strontium

Boivin, G., et al. 2010. In osteoporotic women treated with strontium ranelate, strontium is located in bone formed during treatment with a maintained degree of mineralization. Osteoporos Int., 21 (4), 667–677. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19597910 (accessed 07.27.2010).

Boonen, S. Addressing the age-related needs of osteoporotic patients with strontium ranelate. Osteoporos. Int., 21 (Suppl. 2), S415–S423. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20464375 (accessed 07.27.2010).

Bünger, M., et al. 2010. Strontium and bone nanostructure in normal and ovariectomized rats investigated by scanning small-angle X-ray scattering. Calcif. Tissue Int., 86 (4), 294–306. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20221590 (accessed 07.27.2010).

Busse, B., et al. 2010. Effects of strontium ranelate administration on bisphosphonate-altered hydroxyapatite: Matrix incorporation of strontium is accompanied by changes in mineralization and microstructure. Acta Biomater. [Epub ahead of print.] URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20654744 (accessed 07.27.2010).

Caudrillier, A., et al. 2010. Strontium ranelate decreases RANKL-induced osteoclastic differentiation in vitro: Involvement of the calcium sensing receptor. Mol. Pharmacol. [Epub ahead of print.] URL: http://molpharm.aspetjournals.org/content/early/2010/06/28/mol.109.063347.long (accessed 07.26.2010).

Deeks, E., & Dhillon, S. 2010. Strontium ranelate: A review of its use in the treatment of postmenopausal osteoporosis. Drugs, 70 (6), 733–759. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20394457 (accessed 07.27.2010).

de Sousa, I., et al. 2010. Short-term bone marker responses to teriparatide and strontium ranelate in patients with osteoporosis previously treated with bisphosphonates. Arq. Bras. Endocrinol. Metabol., 54 (2), 244–249. URL (PDF): http://www.scielo.br/pdf/abem/v54n2/23.pdf (accessed 07.27.2010).

Ferrari, S. 2010. Comparing and contrasting the effects of strontium ranelate and other osteoporosis drugs on microarchitecture. Osteoporos. Int., 21 (Suppl. 2), S437–S442. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20464378 (accessed 07.26.2010).

Fromigué, O., et al. 2010. Essential role of nuclear factor of activated T cells (NFAT)-mediated WNT signalling in osteoblast differentiation induced by strontium ranelate. J. Biol. Chem. [Epub ahead of print.] URL: http://www.jbc.org/content/early/2010/06/16/jbc.M110.110502.long (accessed 07.27.2010).

Li, Z., et al. 2010. The morphology and lattice structure of bone crystal after strontium treatment in goats. J. Bone Miner. Metab., 28 (1), 25–34. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19603246 (accessed 07.26.2010).

Qi, W., et al. 2010. The co-effect of Cordyceps sinensis and strontium on osteoporosis in ovariectomized osteopenic rats. Biol. Trace Elem. Res. [Epub ahead of print.] URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20443075 (accessed 07.27.2010).

Ringe, J., et al. 2010. Efficacy of strontium ranelate on bone mineral density in men with osteoporosis. Arzneimittelforschung, 60 (5), 267–272.URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20533764 (accessed 07.27.2010).

Ringe, J. 2010. Strontium ranelate: An effective solution for diverse fracture risks. Osteoporos. Int., 21 (Suppl. 2), S431–S436. URL: (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20464377 (accessed 07.27.2010)

Rizzoli, R., et al. 2010. Strontium ranelate and alendronate have differing effects on distal tibia bone microstructure in women with osteoporosis. Rheumatol Int., 30 (10), 1341–1348. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20512336 (accessed 07.27.2010).

Roschger, P., et al. 2010. Bone material quality in transiliac bone biopsies of postmenopausal osteoporotic women after 3 years of strontium ranelate treatment. J. Bone Miner. Res., 25 (4), 891–900. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20437609 (accessed 07.27.2010).

Seeman, E., et al. 2010. Five years treatment with strontium ranelate reduces vertebral and nonvertebral fractures and increases the number and quality of remaining life-years in women over 80 years of age. Bone, 46 (4), 1038–1042. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20026265 (accessed 05.17.2010).

Sun, P., et al. 2010. Effects of alendronate and strontium ranelate on cancellous and cortical bone mass in glucocorticoid-treated adult rats. Calcif. Tissue Int. 86 (6), 495–501. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20390406 (accessed 07.27.2010).

Takaoka, S., et al. 2010. The calcium-sensing receptor (CaR) is involved in strontium ranelate-induced osteoblast differentiation and mineralization. Horm. Metab. Res. [Epub ahead of print.] URL: http://www.ncbi.nlm.nih.gov/pubmed/20560105 (accessed 07.27.2010).

Brennan, T., et al. 2009. Osteoblasts play key roles in the mechanisms of action of strontium ranelate. Br. J. Pharmacol., 157 (7), 1291–1300. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19563530 (accessed 07.27.2010).

Li, Z., et al. 2009. Strontium-calcium coadministration stimulates bone matrix osteogenic factor expression and new bone formation in a large animal model. J. Orthop. Res., 27 (6), 758-762. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19025756 (accessed 05.17.2010).

Boonen, S., et al. 2008. Osteoporosis and osteoporotic fracture occurrence and prevention in the elderly: A geriatric perspective. Best Pract. Res. Clin. Endocrinol. Metab., 22 (5), 765–785. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19028356 (accessed 12.22.2008).

Lam, S., & Zouzias, K. 2008. Strontium ranelate for the management of osteoporosis. Consult. Pharm., 23 (7), 531–537. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/18764671 (accessed 12.22.2008).

Li, Z., et al. 2008. Strontium–calcium coadministration stimulates bone matrix osteogenic factor expression and new bone formation in a large animal model. J. Orthop. Res., 27 (6), 758–762. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19025756 (accessed 12.22.2008).

Alexandersen, P., et al. 2007. Strontium ranelate reduces the urinary level of cartilage degradation biomarker CTX-II in postmenopausal women. Bone, 40 (1), 218–222. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/17010685 (accessed 12.22.2008).

Boonen, S. 2006. Addressing and meeting the needs of osteoporotic patients with strontium ranelate: A review. Curr. Opin. Rheumatol., 18 (Suppl. 1), S21–S27. Review. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/16735842 (accessed 12.22.2008).

Marie, P. 2006. Strontium ranelate: A physiological approach for optimizing bone formation and resorption. Bone, 38 (2 Suppl. 1), S10–S14. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/16439191 (accessed 12.22.2008).

O’Donnell, S., et al. 2006. Strontium ranelate for preventing and treating postmenopausal osteoporosis. Cochrane Database Syst. Rev., 3, CD005326. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/17054253 (accessed 12.18.2008).

Compston, J. 2005. Prevention of vertebral fractures by strontium ranelate in postmenopausal women with osteoporosis. Osteoporos. Int., 16 (Suppl. 1), S4–S6. Review. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/15480571 (accessed 12.22.2008).

Hamdy, R., et al. 2005. Review of treatment modalities for postmenopausal osteoporosis. South. Med. J., 98 (10), 1000–1014; quiz 1015–1017, 1048. Review. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/16295815 (accessed 12.22.2008).

Reginster, J., et al. 2004. Strontium ranelate: A new paradigm in the treatment of osteoporosis. Expert Opin. Investig. Drugs, 13 (7), 857–864. Review. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/12698204 (accessed 05.20.2008).

Rovenský, J., et al. 2003. Eggshell calcium in the prevention and treatment of osteoporosis. Int. J. Clin. Pharmacol. Res., 23 (2–3), 83–92. Review. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/15018022 (accessed 12.22.2008).

Reginster, J. 2002. Strontium ranelate in osteoporosis. Curr. Pharm. Des., 8 (21), 1907–1916. URL (abstract): http://informahealthcare.com/doi/abs/10.1517/13543784.13.7.857%20 (accessed 12.22.2008).

Schaafsma, A., et al. 2000. Mineral, amino acid, and hormonal composition of chicken eggshell powder and the evaluation of its use in human nutrition. Poult. Sci., 79 (12), 1833–1838. URL: http://ps.fass.org/cgi/reprint/79/12/1833 (accessed 12.22.2008).

Morohashi, T., et al. 1995. Effects of strontium on calcium metabolism in rats. II. Strontium prevents the increased rate of bone turnover in ovariectomized rats. Jpn. J. Pharmacol., 68 (2), 153–159. URL (PDF): http://www.journalarchive.jst.go.jp/jnlpdf.php?cdjournal=jphs1951&cdvol=68&noissue=2&startpage=153&lang=en&from=jnlabstract (accessed 12.22.2008).

Kollenkirchen, U. 1995. Measurement of bone resorption by strontium excretion in prelabelled rats. Bone, 17 (4 Suppl.), 455S–460S. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/8579952 (accessed 12.22.2008).

Gaby, A. 1994. Preventing and Reversing Osteoporosis: What You Can Do About Bone Loss — A Leading Expert’s Natural Approach to Increasing Bone Mass. Roseville, CA: Prima Publishing.

Skoryna, S. 1981. Effects of oral supplementation with stable strontium. CMAJ, 125 (7), 703–712. URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1862446/ (accessed 09.01.2010).

Storey, E. 1961. Strontium “rickets”: Bone, calcium and strontium changes. Aust. Ann. Med., 10, 213–222. URL (no abstract available): http://www.ncbi.nlm.nih.gov/pubmed/13917518 (accessed 09.01.2010).

Shorr, E., & Carter, A. 1950. The value of strontium as an adjuvant to calcium in the mineralization of the skeleton in osteoporosis in man. In Reifenstein, C., & Johnson, (eds.): Metabolic Interrelations: Transactions of the Second Conference, January 9-10, 1950, pp. 144-154. Josiah Macy, Jr. Foundation, New York.

McCaslin, F., & Janes, J. 1959. The effect of strontium lactate in the treatment of osteoporosis. Proc. Staff Meet. Mayo Clin., 34, 329-334.